Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7
نویسندگان
چکیده
منابع مشابه
Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7.
Bone marrow transplantation (BMT) is followed by a period of profound immune deficiency, during which new T lymphocytes are generated from either stem cells or immature thymic progenitors. Interleukin-7 (IL-7) induces proliferation and differentiation of immature thymocytes. We examined whether the in vivo administration of IL-7 to mice receiving BMT would alter thymic reconstitution. Lethally ...
متن کاملRadiosensitivity of thymic interleukin-7 production and thymopoiesis after bone marrow transplantation.
Interleukin-7 (IL-7) is the major thymopoietic cytokine. Injections of IL-7 after murine bone marrow transplantation (BMT) correct defects in thymic differentiation, including thymic hypocellularity, abnormal differentiation of CD3- CD4- CD8- (triple-negative [TN]) thymocytes into CD4+ CD8+ (double-positive [DP]) cells, and antigen-specific mature T-lymphocyte proliferation. To determine whethe...
متن کاملNurse and Bone Marrow Transplant
پیوند مغز استخوان باید به مدت طولانی در بیمارستان بستری باشند، که این امر نیز موجب بروز برخی از عوارض روانی مانند: افسردگی، اضطراب، کج خلقی، ترس و ناامیدی در آنان خواهد شد. هرچند که برخورد صحیح کادر مراقبتی درمانی می تواند تا حد زیادی از این عوارض پیشگیری کند. در این مسیر تقویت اعتماد، اعتقاد، امید و تلاش برای سازگاری با مشکل ضرورت دارد. امروزه بسیاری از بیماریهای بدخیم به درمان با پیوند مغز اس...
متن کاملThe Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases
Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
متن کاملBone Marrow Transplant (BMT) is the Main Cureavailable for Thalassamia
Introduction: The thalassamias refer to a diverse group of hemoglobin disorders characterized by a reduced synthesis of one or more of globin chains (α,β, γ, δβ,γδβ, δ and εγδβ).The main cure available today for thalassamia is bone marrow transplantation (BMT) from compatible donor.On December 3, 1981 a 14-month-old child with β-thalassemia major recieved BMT from his HLA-identical sister in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 1996
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v88.5.1887.1887